AZIZIYAH Medical Centre

AZIZIYAH Medical Centre
AMC

Wednesday, January 29, 2025

Free Lung Cancer Screening .,.



Importance of Screening in Lung Cancer

Lung cancer is one of the leading causes of cancer-related deaths worldwide, and early detection through screening significantly improves survival rates. Below are the key reasons why lung cancer screening is crucial:

1. Early Detection and Improved Survival Rates

Lung cancer is often asymptomatic in its early stages, leading to late diagnoses when treatment options are limited.

Screening, particularly with low-dose computed tomography (LDCT), helps detect lung cancer at an earlier, more treatable stage.

Studies, including the National Lung Screening Trial (NLST) and the NELSON trial, have shown that LDCT screening reduces lung cancer mortality by 20–24% in high-risk individuals.


2. Higher Treatment Success and Reduced Mortality

When lung cancer is diagnosed at Stage I, the 5-year survival rate is about 60–90%. In contrast, late-stage detection (Stage IV) has a survival rate of less than 10%.

Screening enables early intervention, increasing the chances of successful treatment through surgery, radiation, or targeted therapies.


3. Cost-Effectiveness of Preventive Screening

Treating advanced-stage lung cancer is significantly more expensive than treating early-stage disease.

Early detection reduces healthcare costs by allowing less invasive, more effective treatments.


4. Identification of High-Risk Individuals

Lung cancer screening is recommended primarily for:

Adults aged 50–80 years (as per USPSTF guidelines).

Those with a 30-pack-year smoking history (i.e., smoking one pack per day for 30 years or two packs per day for 15 years).

Current smokers or those who quit within the past 15 years.


5. Prevention of Advanced Disease and Metastasis

Lung cancer metastasizes quickly, often spreading to the brain, liver, or bones before symptoms appear.

Early detection through LDCT prevents disease progression and enhances the quality of life.


6. Public Health Impact

Large-scale screening programs can significantly reduce the lung cancer burden.

Countries like the U.S. and U.K. have implemented screening programs that have already demonstrated a reduction in lung cancer mortality.


Limitations and Risks of Screening

False Positives: Some LDCT scans may detect benign nodules, leading to unnecessary tests and anxiety.

Radiation Exposure: LDCT involves minimal radiation, but repeated scans pose a slight risk.

Overdiagnosis: Some slow-growing cancers may not have caused harm if left undetected, yet they may still be treated.


Conclusion

Lung cancer screening, particularly with low-dose CT scans, plays a crucial role in reducing mortality and improving patient outcomes. While not risk-free, the benefits far outweigh the drawbacks, making screening essential for high-risk individuals. Expanding awareness and access to lung cancer screening programs can save thousands of lives annually.

Friday, January 24, 2025

Free Lung Cancer Screening at AZIZIYAH Medical Centre Bathindi Jammu.



Lung cancer screening and early diagnosis are critical for improving outcomes. Here are some tips and guidelines:

1. Know the Risk Factors

Smoking: The most significant risk factor. Screening is highly recommended for current or former smokers.

Secondhand Smoke: Prolonged exposure increases risk.

Environmental Exposures: Radon gas, asbestos, and air pollution contribute to lung cancer risk.

Family History: A genetic predisposition can elevate risk.


2. Eligibility for Screening

Screening is typically recommended for:

Adults aged 50-80.

Those with a 20 pack-year smoking history (e.g., smoking one pack daily for 20 years).

Current smokers or those who quit within the last 15 years.



3. Screening Methods

Low-Dose Computed Tomography (LDCT):

Most effective for detecting lung cancer early.

Involves low radiation exposure.


Avoid chest X-rays for screening; they are less sensitive.


4. Early Symptoms to Watch For

Persistent cough (especially if it worsens).

Coughing up blood.

Shortness of breath or wheezing.

Chest pain that worsens with deep breathing or coughing.

Unexplained weight loss and fatigue.


5. Lifestyle Modifications for Prevention

Quit smoking immediately. Seek professional help or use nicotine replacement therapy if needed.

Test your home for radon.

Limit exposure to workplace carcinogens with protective gear.

Maintain a healthy diet and regular exercise routine.


6. Consult Your Doctor

Discuss your risk factors with a healthcare provider.

Ensure regular follow-ups if you are at high risk.


7. Be Proactive About Health

Encourage regular check-ups, especially if you have a history of smoking or other risk factors.

Promote awareness about lung cancer in your community.


Early detection saves lives. If you or someone you know meets the criteria for screening, consider scheduling an LDCT.

Tuesday, January 21, 2025

ASCO Lung Cancer Screening ...guidlines



Lung cancer is the leading cause of mortality and person-years of life lost from cancer among US men and women. Early detection has been shown to be associated with reduced lung cancer mortality. Our objective was to update the American Cancer Society (ACS) 2013 lung cancer screening (LCS) guideline for adults at high risk for lung cancer. The guideline is intended to provide guidance for screening to health care providers and their patients who are at high risk for lung cancer due to a history of smoking. The ACS Guideline Development Group (GDG) utilized a systematic review of the LCS literature commissioned for the US Preventive Services Task Force 2021 LCS recommendation update; a second systematic review of lung cancer risk associated with years since quitting smoking (YSQ); literature published since 2021; two Cancer Intervention and Surveillance Modeling Network-validated lung cancer models to assess the benefits and harms of screening; an epidemiologic and modeling analysis examining the effect of YSQ and aging on lung cancer risk; and an updated analysis of benefit-to-radiation-risk ratios from LCS and follow-up examinations. The GDG also examined disease burden data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results program. Formulation of recommendations was based on the quality of the evidence and judgment (incorporating values and preferences) about the balance of benefits and harms. The GDG judged that the overall evidence was moderate and sufficient to support a strong recommendation for screening individuals who meet the eligibility criteria. LCS in men and women aged 50–80 years is associated with a reduction in lung cancer deaths across a range of study designs, and inferential evidence supports LCS for men and women older than 80 years who are in good health. The ACS recommends annual LCS with low-dose computed tomography for asymptomatic individuals aged 50–80 years who currently smoke or formerly smoked and have a ≥20 pack-year smoking history (strong recommendationmoderate quality of evidence). Before the decision is made to initiate LCS, individuals should engage in a shared decision-making discussion with a qualified health professional. For individuals who formerly smoked, the number of YSQ is not an eligibility criterion to begin or to stop screening. Individuals who currently smoke should receive counseling to quit and be connected to cessation resources. Individuals with comorbid conditions that substantially limit life expectancy should not be screened. These recommendations should be considered by health care providers and adults at high risk for lung cancer in discussions about LCS. If fully implemented, these recommendations have a high likelihood of significantly reducing death and suffering from lung cancer in the United States.

INTRODUCTION

In 1980, the American Cancer Society (ACS) withdrew a prior recommendation for regular lung cancer screening (LCS) with chest radiography (CXR) in persons who currently or formerly smoked because a series of randomized controlled trials (RCTs) conducted in the 1970s had not demonstrated convincing evidence that LCS saved lives.1 Thirty-three years later, after publication of the National Lung Screening Trial (NLST) (ClinicalTrials.gov identifier NCT00047385) demonstrating that three rounds of annual LCS with low-dose computed tomography (LDCT) were associated with a 20% relative mortality reduction compared with annual LCS with CXR,2 the ACS issued a recommendation for annual screening with LDCT in adults who met the eligibility requirement for the NLST (i.e., individuals aged 55–74 years with a 30 or greater pack-year history of smoking who currently smoke, or formerly smoked and had not exceeded 15 years since smoking cessation, and did not have life-limiting comorbidity).3 In this update of the 2013 LCS guideline, the ACS Guideline Development Group (GDG) addresses a broad spectrum of issues related to LCS, including the most recent evidence on the efficacy and effectiveness of LCS, the lung cancer risk in persons who formerly smoked and have exceeded 15 years since cessation, estimates of the benefits and harms of screening past age 80 years and screening in eligible adults with greater than 5 years of longevity, and updated benefit-to-radiation-risk ratios based on modern doses from ionizing radiation from screening and follow-up examinations. We also discuss the challenges of implementing LCS, enduring disparities in disease burden and screening rates, and the urgent need to significantly improve utilization and adherence to screening and follow-up testing among qualifying individuals.

In this update of LCS, the ACS recommends that individuals aged 50–80 years who currently smoke or who formerly smoked and are at high risk for lung cancer because of a 20 or greater pack-year history of cigarette smoking undergo annual LCS with LDCT (Tables 1 and 2). We also recommend against using any duration of years since quitting smoking (YSQ) as a criterion to begin or end LCS in individuals who formerly smoked and who meet age and pack-year eligibility criteria. Individuals who smoke should be advised to quit and offered evidence-based smoking-cessation interventions. Existing comorbid conditions that may limit life expectancy or the inability or unwillingness to undergo evaluation of positive screening findings or to undergo treatment are factors that should preclude referrals for screening. Because of these considerations, the risks associated with LCS, and the relative newness of LCS to the target population, potentially eligible individuals should undergo a process of shared decision-making (SDM) that includes a discussion about the purpose of LCS, the consensus among leading organizations on recommendations endorsing LCS; the screening process and the importance of regular screening; the benefits, limitations, and potential harms of screening; and consideration of patient values and preferences. We also discuss the challenges of implementing LCS, enduring disparities in disease burden and screening rates, and the urgent need to significantly improve utilization and adherence to screening and follow-up testing among qualifying individuals. This guideline for LCS is based on the underlying burden of disease, an assessment of the strength of evidence, the balance of benefits and harms, and consideration of patient values and preferences.

TABLE 1. American Cancer Society guideline for lung cancer screening, 2023.
These recommendations represent updated guidance from the American Cancer Society for asymptomatic persons who are at high risk of lung cancer based on cumulative exposure to tobacco by smoking.
Recommendation
The American Cancer Society recommends annual screening for lung cancer with low-dose computed tomography in asymptomatic individuals aged 50 to 80 years who currently smoke or formerly smoked and have a ≥20 pack-yeara smoking history (strong recommendation b; moderate quality evidence).

Sunday, January 19, 2025

Free Lung Cancer Screening Month....


State of Lung Cancer in 20204

Introduction
About every two minutes, someone in the U.S. is diagnosed with lung cancer, and every day, lung cancer takes the lives 
of 361 of our friends, neighbors and loved ones. But now there’s hope as more people in America than ever are surviving 
lung cancer. While the disease remains the leading cause of cancer deaths, over the past five years, the survival rate has 
increased by 26% nationally to 28.4%.
This year’s report also examines the lifesaving potential of lung cancer screening, which can detect the disease at an 
earlier stage when it’s more curable, the importance of advancements in lung cancer research, which holds the promise 
for better treatment options, and insurance coverage of comprehensive biomarker testing, which can help determine 
what treatment options would be best for individuals with lung cancer and other diseases.
In March of 2021, the United States Preventive Services Task Force expanded its recommendation for screening to 
include a larger age range and more current and former smokers. This dramatically increased the number of women and 
Black individuals who are considered at high risk for lung cancer. Unfortunately, in 2022, only 16.0% of all those eligible 
were screened.
For the fifth consecutive year, the “State of Lung Cancer” report explores the lung cancer burden among racial and 
ethnic groups at the national and state levels. In addition to lower survival rates, people of color who are diagnosed with 
lung cancer face worse outcomes compared to white individuals: they are less likely to be diagnosed early, less likely to 
receive surgical treatment, and more likely to not receive any treatment.
A strategic imperative of the American Lung Association is to defeat lung cancer, and to do so, we use a variety of tactics 
and work with diverse stakeholders to address the disease and its risk factors, including public policy efforts and public 
health protections, awareness of lung cancer screening and more.
The “State of Lung Cancer” report provides a state-specific understanding of the burden of lung cancer and opportunities 
to address this deadly disease.
The report also serves as both a guidepost and rallying call, providing policymakers, researchers, healthcare practitioners, 
as well as people diagnosed with lung cancer, caregivers and others committed to ending lung cancer by identifying 
where their state can best focus its resources to decrease the toll of lung cancer.

Cancer on Rise in Jammu region..